Severe Anaphylactic Reaction to Thiopentone: Case Report

Severe anaphylactic reaction to thiopentone: case report.

In view of the estimated millions of thiopentone injections given annually, and the frequent reports of cutaneous manifestations of allergy to barbiturate drugs, it is surprising that anaphylaxis to barbiturates is so rarely reported. We believe that some cases may be unrecognized or misdiagnosed. A woman of 58 with carcinoma of the bladder had been treated seven years previously, in 1958, by t...

Anaphylactic reaction to pemetrexed: a case report.

Pemetrexed is approved to treat non-small cell lung cancer and has an overall favorable toxicity profile. We describe a 58-year-old man who developped an anaphylactic shock within few minutes from the beginning of pemetrexed perfusion. Pemetrexed was discontinued and the patient's symptoms gradually resolved with administration of symptomatic treatment. Serum tryptase level remained normal and ...

Severe anaphylactic reaction to mediterranean jellyfish (Ropilhema nomadica) envenomation: Case report

We present a 15-year-old female patient with an anaphylactic reaction to a jellyfish sting, sustained while surfing in the Mediterranean Sea. She experienced immediate difficulty in breathing, hoarseness and itching and was taken by ambulance to the emergency department, receiving intramuscular adrenaline on the way. She presented with periorbital swelling and facial edema and improved with sys...

Case report: severe neurologic reaction to ciprofloxacin.

Severe anaphylactic reaction at induction of anaesthesia.

Anaphylaxis is an IgE mediated severe allergic reaction causing release of vasoactive substances from mast cells and basophils after re-exposure to an antigen. Signs and symptoms include flushing, urticaria, hypotension, tachycardia, bronchospasm, cardio-respiratory arrest etc. It can occur at induction of anaesthesia when multiple drugs are being administered, but prompt diagnosis with correct...